Original Research Paper

Epidural Alkalinized Ropivacaine 0.2% For Postoperative Pain Relief Primarily On Onset And Duration Of Analgesia

Abstract :

Introduction: Postoperative pain management is crucial to promote better recovery and overall wellbeing of the patient. The addition of an alkaline substance to local anesthetics is believed to facilitate quicker penetration into nerves, but the literature is inconclusive. Ropivacaine is a long-acting local anesthetic that is increasingly used for postoperative pain management. This study aimed to evaluate the onset and duration of analgesia after single shot epidural dose of ropivacaine 0.2% with or without the addition of an alkaline substance.Objective: The study aimed to determine the time of onset and duration of analgesia after single shot epidural dose of ropivacaine 0.2%.Materials and Methods: The prospective study was conducted at a hospital for a year, involving 90 adult patients. Patients were randomly assigned to one of three groups: Group A received plain ropivacaine 0.2%, Group B received alkalinized ropivacaine 0.2%, and Group C received alkalinized ropivacaine 0.2% and clonidine 37.5mcg. The onset and duration of analgesia were assessed by monitoring the Visual Analog Scale (VAS) score, sensory block level, and duration of motor block.Results: The duration of surgery did not differ significantly among the groups. However, the time of onset of analgesia was significantly different among the groups, with a mean of 24.23.96 mins for Group A, 8.061.63 mins for Group B, and 7.561.16 mins for Group C (p

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